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Prednisone is a synthetic, cortisol-derived anti-inflammatory glucocorticoid. The substances that are broken down are converted into prednisone by the liver, thus making it biologically inert. The delayed-release drug corticosteroid drug Prednisone has been approved by the FDA for clinical usage as an anti-inflammatory or immunosuppressive medication that aids in the treatment of a wide range of conditions.

Some of the conditions that can be treated using this drug are rheumatic, immunosuppressive/endocrine, dermatologic, allergic states, neoplastic, edematous, collagen, respiratory, gastrointestinal (GI), acute exacerbations of multiple sclerosis, ophthalmic, and hematologic. The medication prednisone belongs to a class of drugs known as corticosteroids. It relieves allergic reactions, swelling, redness, and itching by working on the immune system. Only prescriptions are accepted for this medication.

Prednisone is frequently prescribed for purposes other than those listed on the label, or in a dosage that differs from that listed. These are referred to as non-FDA-approved indications or off-label prescribing. How does it work? Other nations may use terms like “approved” or “licensed” that do not apply in the United States.

Prednisone and other steroid medications work by slowing down the immune system.

Your body’s defense system is your immune system. Steroids work by slowing down your body’s response to illness or injury. Some immune-related symptoms, like swelling and inflammation, can be reduced with prednisone.

What is the purpose of prednisone?

Many different diseases can be treated with prednisone, including:

  • Because it can lessen your immune system’s response to the new kidney, prednisone can also help prevent organ rejection following a kidney transplant for certain types of arthritis and asthma. A transplanted organ is seen by the body as a foreign mass. The immune system of the body responds by attacking it as a result of this.
  • Other kidney conditions that can be treated with prednisone include:
  • Nephrotic syndrome: Results from focal glomerulosclerosis (FSGS), IGA nephropathy. As a result, the urine contains a significant amount of protein. As a result, proteinuria, or a lack of protein in the blood, develops. In these conditions, prednisone is used to help reduce proteinuria.

What negative effects does prednisone have?

Prednisone, on the other hand, may also have negative effects. Some examples include:

  • Acne
  • Swelling (face, hands, arms,  feet, or lower legs)
  • Weight gain
  • Fatigue
  • Changes in appetite
  • Dizziness
  • Can prednisone aggravate other health conditions?
  • Changes in mood
  • Headaches
  • Slowed healing of cuts and bruises

Prednisone users may also experience an increase in blood sugar, which is especially concerning for diabetics. Prednisone can also raise the risk of infection because it suppresses the body’s immune system.To avoid adverse outcomes, there needs to be certain measures taken.

Discuss the following with your healthcare provider before taking prednisone:

  • If you have been prescribed prednisone or any other steroid medication in the past and have experienced an allergic reaction, or if you are currently on any other prescribed pills.
  • have diabetes or increased blood pressure.
  • Pregnant or planning to get pregnant
  • What can I do to maintain my health while taking prednisone?
  • When prescribing this and other medications, your healthcare provider will weigh the potential benefits and negative effects. Prednisone has helped a lot of people without causing major side effects. Prednisone can be beneficial to you while you manage side effects if you talk to your doctor, take your medication as directed, and follow the instructions.

You can take steps to maintain your health in the following ways:

  • Follow the directions on your prescription.
  • Do not take two doses at once. If you miss a dose, ask your doctor or nurse what to do.
  • If you feel that you have attained the desired effects and no longer need the medication, tell your doctor so. On their approval, you can stop its usage by gradually decreasing the dosage amount. Prednisone is typically tapered, or reduced gradually, to prevent withdrawal symptoms. Sudden discontinuation of prednisone use can result in withdrawal symptoms such as:
  • The salt and sugar intake in your diet can be reduced to prevent fatigue and dramatic mood swings.
  • Be aware of your weight.
  • If you experience any sudden or unusual symptoms, such as vision issues, dizziness, irregular heartbeat, or shortness of breath, you should talk to your doctor.